{"id":1961,"date":"2009-06-12T19:45:17","date_gmt":"2009-06-12T10:45:17","guid":{"rendered":"http:\/\/alm-ore.com\/blog\/archives\/2009\/06\/post_1157.html"},"modified":"2015-12-25T12:06:03","modified_gmt":"2015-12-25T03:06:03","slug":"post_1157","status":"publish","type":"post","link":"https:\/\/alm-ore.com\/blog\/archives\/2009\/06\/post_1157.html","title":{"rendered":"\u76ee\u304b\u3089\u65e5\u713c\u3051\u3059\u308b\u3063\u3066\u8a71: \u95a2\u9023\u8ad6\u6587\u3092\u8aad\u3093\u3060"},"content":{"rendered":"<p>\u4f8b\u306e\u300c\u76ee\u306b\u7d2b\u5916\u7dda\u3092\u7167\u5c04\u3059\u308b\u3068\u3001\u305d\u306e\u4ed6\u306e\u76ae\u819a\u306b\u65e5\u713c\u3051\u304c\u8d77\u304d\u308b\u300d\u3068\u3044\u3046\u8a71\u306b\u95a2\u3057\u3066\u3001\u95a2\u9023\u8ad6\u6587\u3092\u8aad\u3093\u3067\u307f\u305f\u3002<br \/>\n\u4e57\u308a\u639b\u304b\u3063\u305f\u8239\u306a\u306e\u3067\u3001\u7c21\u5358\u306a\u30e1\u30e2\u3092\u4f5c\u3063\u3066\u304a\u304f\u3002<\/p>\n<p>K. Hiramoto, N. Yanagihara, EF. Sato, M. Inoue: Ultraviolet B irradiation of the eye activates a nitric oxide-dependent hypothalamopituitary proopiomelanocortin pathway and modulates functions of alpha-melanocyte-stimulating hormone-responsive cells. <i>Journal of Investigative Dermatology<\/i>, <b>120<\/b>, 123-127, 2003.\uff08\u30c0\u30a6\u30f3\u30ed\u30fc\u30c9\uff09<\/p>\n<p><!--more--><br \/>\n\u88ab\u691c\u4f53\u306f\u30cd\u30ba\u30df\u3002<br \/>\n\u5f7c\u3089\u306f\u9ebb\u9154\u3092\u304b\u3051\u3089\u308c\u3001\u5168\u8eab\u3092\u30a2\u30eb\u30df\u30db\u30a4\u30eb\u3067\u5305\u307e\u308c\u308b\u3002\u500b\u4f53\u3054\u3068\u306b\u76ee\u3001\u8033\u3001\u80cc\u4e2d\u306e\u3044\u305a\u308c\u304b\u306e\u8986\u3044\u304c\u306f\u304c\u3055\u308c\u3001\u305d\u3053\u306b\u7d2b\u5916\u7dda\u304c\u7167\u5c04\u3055\u308c\u308b\u3002\u5bfe\u7167\u7fa4\u3068\u3057\u3066\u3001\u540c\u3058\u90e8\u5206\u306b\u53ef\u8996\u5149\u3092\u7167\u5c04\u3055\u308c\u308b\u7fa4\u3092\u7528\u610f\u3057\u305f\u3002\uff08\u5149\u7dda\u306e\u6ce2\u9577\u3084\u767a\u751f\u3059\u308b\u30a8\u30cd\u30eb\u30ae\u30fc\u306b\u3064\u3044\u3066\u306e\u8a18\u8ff0\u3092\u898b\u3064\u3051\u305f\u304c\u3001\u7167\u5c04\u6642\u9593\u306b\u95a2\u3057\u3066\u50d5\u306f\u898b\u3064\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u306a\u304b\u3063\u305f\uff09\u3002<\/p>\n<p>\u7167\u5c04\u304b\u30895\u65e5\u5f8c\u3001\u30cd\u30ba\u30df\u304b\u3089\u76ae\u819a\uff08\u57fa\u672c\u7684\u306b\u8033\uff09\u3092\u63a1\u53d6\u3057\u3001\u30e1\u30e9\u30cb\u30f3\u7d30\u80de\u304c\u3069\u308c\u3060\u3051\u3067\u304d\u3066\u3044\u308b\u304b\u8abf\u3079\u308b\u3002\u4e0b\u306e\u5199\u771f\u306e\u3088\u3046\u306b\u3001\u30e1\u30e9\u30cb\u30f3\u7d30\u80de\u306e\u767a\u751f\u6570\u304c\u7570\u306a\u308b\u305d\u3046\u3060\u3002\u5de6\u304b\u3089\u5bfe\u7167\u7fa4\u3001\u76ee\u306b\u7d2b\u5916\u7dda\u3001\u8033\u306b\u7d2b\u5916\u7dda\u3002<\/p>\n<p><span style=\"display: inline;\"><a href=\"https:\/\/alm-ore.com\/blog\/archives\/2009\/06\/12\/Fig1.jpg\"><img loading=\"lazy\" decoding=\"async\" alt=\"Hiramoto et al., 2003; Fig1: \u30e1\u30e9\u30cb\u30f3\u7d30\u80de\u306e\u5199\u771f\" src=\"https:\/\/alm-ore.com\/blog\/archives\/assets_c\/2009\/06\/Fig1-thumb-250x184.jpg\" width=\"250\" height=\"184\" style=\"text-align: center; display: block; margin: 0 auto 20px;\" \/><\/a><\/span><\/p>\n<p>\u4e0b\u306b\u3042\u308b\u306e\u306f\u5b9f\u9a13\u7d50\u679c\u306e\u30b0\u30e9\u30d5\u3002\u7e26\u8ef8\u306f\u751f\u6210\u3055\u308c\u305f\u30e1\u30e9\u30cb\u30f3\u7d30\u80de\u306e\u6570\u3092\u8868\u3059\u3002<\/p>\n<p>\u767d\u3044\u30d0\u30fc\u306f\u3001\u4f55\u3082\u64cd\u4f5c\u3092\u304a\u3053\u308f\u306a\u304b\u3063\u305f\u30cd\u30ba\u30df\u3002&#8221;Visible&#8221; \u3068\u66f8\u304b\u308c\u3066\u3044\u308b2\u672c\u306f\u53ef\u8996\u5149\u3092\u7167\u5c04\u3055\u308c\u305f\u5bfe\u7167\u7fa4\u3067\u3042\u308a\u3001\u672a\u64cd\u4f5c\u7fa4\u3068\u540c\u3058\u6c34\u6e96\u3002\u3064\u307e\u308a\u3001\u7d2b\u5916\u7dda\u304c\u7167\u5c04\u3055\u308c\u306a\u3051\u308c\u3070\u3001\u65e5\u713c\u3051\uff08\u30e1\u30e9\u30cb\u30f3\u751f\u6210\uff09\u306f\u8d77\u304d\u306a\u3044\u3002\u5f53\u305f\u308a\u524d\u3002<\/p>\n<p>&#8220;UVB&#8221; \u306e3\u672c\u306e\u30d0\u30fc\u306f\u3001\u7d2b\u5916\u7dda\u304c\u7167\u5c04\u3055\u308c\u305f\u7fa4\u3002\u5de6\u306e3\u672c\u306b\u6bd4\u3079\u308b\u3068\u5024\u304c\u9ad8\u304f\u3001\u78ba\u304b\u306b\u7d2b\u5916\u7dda\u306b\u3088\u3063\u3066\u30e1\u30e9\u30cb\u30f3\u7d30\u80de\u304c\u4f5c\u3089\u308c\u3066\u3044\u308b\u3002\u8033\u306e\u76ae\u819a\u3092\u63a1\u53d6\u3057\u305f\u306e\u3067\u3001\u78ba\u304b\u306b\u8033\u306b\u7d2b\u5916\u7dda\u3092\u5f53\u3066\u3089\u308c\u305f\u7fa4(Ear)\u306b\u304a\u3044\u3066\u4e00\u756a\u5024\u304c\u9ad8\u3044\u3002\u3057\u304b\u3057\u9762\u767d\u3044\u306e\u306f\u3001\u80cc\u4e2d\u306b\u7167\u5c04\u3055\u308c\u305f\u7fa4(Dorsal skin)\u3088\u308a\u3082\u3001\u76ee(Eye)\u306b\u7167\u5c04\u3055\u308c\u305f\u7fa4\u306e\u65b9\u304c\u9ad8\u304f\u306a\u3063\u3066\u3044\u308b\u3053\u3068\u3002<br \/>\n\u3053\u306e\u7d50\u679c\u3092\u3082\u3063\u3066\u3001\u300c\u76ee\u304c\u7d2b\u5916\u7dda\u306b\u66dd\u9732\u3055\u308c\u308b\u3068\u3001\u65e5\u713c\u3051\u304c\u8d77\u304d\u308b\u300d\u3068\u3044\u3046\u73fe\u8c61\u306e\u5b58\u5728\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n<p><span style=\"display: inline;\"><a href=\"https:\/\/alm-ore.com\/blog\/archives\/2009\/06\/12\/Fig2.jpg\"><img loading=\"lazy\" decoding=\"async\" alt=\"Hiramoto et al., 2003; Fig2: \u76ee\u306b\u7d2b\u5916\u7dda\u3092\u7167\u5c04\u3057\u305f\u7fa4\u3067\u3082\u3001\u8033\u306b\u30e1\u30e9\u30cb\u30f3\u7d30\u80de\u304c\u4f5c\u3089\u308c\u3066\u3044\u308b\u3002\u80cc\u4e2d\u306b\u7167\u5c04\u3057\u305f\u7fa4\u3088\u308a\u3082\u591a\u3044\" src=\"https:\/\/alm-ore.com\/blog\/archives\/assets_c\/2009\/06\/Fig2-thumb-250x285.jpg\" width=\"250\" height=\"285\" style=\"text-align: center; display: block; margin: 0 auto 20px;\" \/><\/a><\/span><\/p>\n<p>\u6b21\u306b\u3001\u8133\u4e0b\u5782\u4f53\u3092\u6458\u51fa\u3057\u305f\u30cd\u30ba\u30df\u3092\u7528\u3044\u3066\u7d2b\u5916\u7dda\u7167\u5c04\u5b9f\u9a13\u3092\u884c\u3063\u305f\u3002\u305d\u308c\u304c\u6b21\u306e\u30b0\u30e9\u30d5\u3002<br \/>\n\u5de6\u306b\u3042\u308b &#8220;Sham-operated&#8221; \u3068\u3044\u3046\u306e\u306f\u5bfe\u7167\u7fa4\u3067\u3001\u6458\u51fa\u624b\u8853\u3092\u3057\u3066\u3044\u306a\u3044\u7fa4\u3002\u3053\u3061\u3089\u3067\u306f\u3001\u5148\u307b\u3069\u306e\u5b9f\u9a13\u3068\u540c\u3058\u30d1\u30bf\u30fc\u30f3\uff08\u76ee\u306b\u7167\u5c04\u3057\u3066\u3082\u30e1\u30e9\u30cb\u30f3\u304c\u5897\u3048\u308b\uff09\u304c\u5f97\u3089\u308c\u3066\u3044\u308b\u3002<\/p>\n<p>\u4e00\u65b9\u3001\u53f3\u306b\u3042\u308b\u306e\u306f\u8133\u4e0b\u5782\u4f53\u3092\u6458\u51fa\u3057\u305f\u7fa4\u3002\u3059\u308b\u3068\u3001\u76ee\u3092\u7d4c\u7531\u3057\u305f\u30e1\u30e9\u30cb\u30f3\u751f\u6210\u304c\u8d77\u304d\u306a\u304b\u3063\u305f\u3002\u3064\u307e\u308a\u3001\u3010\u76ee\u2192\u8133\u4e0b\u5782\u4f53\u2192\u8033\u306e\u30e1\u30e9\u30cb\u30f3\u3011\u3068\u3044\u3046\u30eb\u30fc\u30c8\u304c\u3042\u308b\u306f\u305a\u306a\u306e\u306b\u3001\u771f\u3093\u4e2d\u306e\u8133\u4e0b\u5782\u4f53\u304c\u306a\u304f\u306a\u3063\u305f\u3053\u3068\u3067\u30eb\u30fc\u30c8\u304c\u9014\u7d76\u3048\u3001\u8033\u3067\u30e1\u30e9\u30cb\u30f3\u304c\u751f\u6210\u3055\u308c\u306a\u304f\u306a\u3063\u305f\u3068\u3044\u3046\u89e3\u91c8\u3002<br \/>\n\u3053\u3053\u304c\u3001\u300c\u76ee\u306b\u3042\u305f\u3063\u305f\u7d2b\u5916\u7dda\u304c\u3001\u8133\u3092\u7d4c\u7531\u3057\u3001\u76ae\u819a\u306e\u65e5\u713c\u3051\u3092\u5f15\u304d\u8d77\u3053\u3059\u300d\u306e\u6839\u62e0\u306b\u306a\u3063\u3066\u3044\u308b\u90e8\u5206\u3002<\/p>\n<p><span style=\"display: inline;\"><a href=\"https:\/\/alm-ore.com\/blog\/archives\/2009\/06\/12\/Fig3.jpg\"><img loading=\"lazy\" decoding=\"async\" alt=\"Hiramoto et al., 2003; Fig3: \u8133\u4e0b\u5782\u4f53\u3092\u6458\u51fa\u3059\u308b\u3068\u3001\u76ee\u306b\u7d2b\u5916\u7dda\u3092\u7167\u5c04\u3057\u3066\u3082\u8033\u306b\u30e1\u30e9\u30cb\u30f3\u7d30\u80de\u306f\u751f\u6210\u3055\u308c\u306a\u3044\" src=\"https:\/\/alm-ore.com\/blog\/archives\/assets_c\/2009\/06\/Fig3-thumb-250x374.jpg\" width=\"250\" height=\"374\" style=\"text-align: center; display: block; margin: 0 auto 20px;\" \/><\/a><\/span><\/p>\n<p>\u4ee5\u4e0a\u3001\u4e3b\u8981\u90e8\u5206\u306e\u307e\u3068\u3081\u3002<\/p>\n<p>\u306a\u304a\u3001\u659c\u3081\u8aad\u307f\u3057\u304b\u3057\u3066\u3044\u306a\u3044\u306e\u3067\u8aad\u307f\u843d\u3068\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3051\u308c\u3069\u3001\u3053\u306e\u8ad6\u6587\u306e\u4e2d\u3067\u306f\u3001\u4eba\u9593\u3067\u3082\u540c\u69d8\u304b\u3069\u3046\u304b\u306f\u8b70\u8ad6\u3055\u308c\u3066\u3044\u306a\u3044\u3002<\/p>\n<p>\u4e0a\u306b\u3082\u66f8\u3044\u305f\u304c\u3001\u7d2b\u5916\u7dda\u306e\u7167\u5c04\u6642\u9593\u306f\u308f\u304b\u3089\u306a\u304b\u3063\u305f\u3002<br \/>\n\u7d2b\u5916\u7dda\u306e\u6ce2\u9577\u306f280-320nm\u3067\u30012.5KJ\/m^2 \u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u3060\u3063\u305f\u305d\u3046\u3060\u3002<br \/>\n\u3053\u308c\u304c\u3069\u306e\u304f\u3089\u3044\u306e\u5f37\u3055\u306e\u7d2b\u5916\u7dda\u306a\u306e\u304b\u50d5\u306b\u306f\u308f\u304b\u3089\u306a\u3044\u306e\u3060\u304c\u3001\u4eba\u9593\u306e\u751f\u6d3b\u74b0\u5883\u3067\u66dd\u9732\u3057\u3046\u308b\u7d2b\u5916\u7dda\u91cf\u306a\u3093\u3060\u308d\u3046\u304b\u3002\u3060\u3068\u3059\u308b\u306a\u3089\u3001\u4eca\u56de\u306e\u5b9f\u9a13\u7d50\u679c\u3092\u771f\u646f\u306b\u53d7\u3051\u6b62\u3081\u3001\u50d5\u3082\u30b5\u30f3\u30b0\u30e9\u30b9\u3092\u304b\u3051\u307e\u304f\u308b\u6240\u5b58\u3002<br \/>\n\u76ee\u306b\u7167\u5c04\u3055\u308c\u305f\u7fa4\u306f\u3001\u8033\u306b\u7167\u5c04\u3055\u308c\u305f\u7fa4\u306e60%\u3050\u3089\u3044\u306e\u91cf\u306e\u30e1\u30e9\u30cb\u30f3\u7d30\u80de\u304c&#8221;\u8033\u306b&#8221;\u751f\u6210\u3055\u308c\u3066\u308b\u3058\u3083\u3093\u3002\u3059\u3052\u3047\u306a\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4f8b\u306e\u300c\u76ee\u306b\u7d2b\u5916\u7dda\u3092\u7167\u5c04\u3059\u308b\u3068\u3001\u305d\u306e\u4ed6\u306e\u76ae\u819a\u306b\u65e5\u713c\u3051\u304c\u8d77\u304d\u308b\u300d\u3068\u3044\u3046\u8a71\u306b\u95a2\u3057\u3066\u3001\u95a2 &hellip; <a href=\"https:\/\/alm-ore.com\/blog\/archives\/2009\/06\/post_1157.html\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"meta-nav\">&rarr;<\/span><\/a> <a href=\"https:\/\/alm-ore.com\/blog\/archives\/2009\/06\/post_1157.html\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2278],"tags":[2434,2431,2432,2427,2428,2433,1668],"class_list":["post-1961","post","type-post","status-publish","format-standard","hentry","category-2278","tag-2434","tag-2431","tag-2432","tag-2427","tag-2428","tag-2433","tag-1668"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/alm-ore.com\/blog\/wp-json\/wp\/v2\/posts\/1961","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/alm-ore.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/alm-ore.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/alm-ore.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/alm-ore.com\/blog\/wp-json\/wp\/v2\/comments?post=1961"}],"version-history":[{"count":0,"href":"https:\/\/alm-ore.com\/blog\/wp-json\/wp\/v2\/posts\/1961\/revisions"}],"wp:attachment":[{"href":"https:\/\/alm-ore.com\/blog\/wp-json\/wp\/v2\/media?parent=1961"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/alm-ore.com\/blog\/wp-json\/wp\/v2\/categories?post=1961"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/alm-ore.com\/blog\/wp-json\/wp\/v2\/tags?post=1961"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}